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Correlation between <t>AAb-IFN-α</t> levels and GADA. Correlation between levels of AAb-IFN-α isoform <t>2b</t> and GAD65 antibodies levels in individuals with LADA who tested positive for AAb-IFN-α2. Spearman's test was fitted to assess the monotonic covariation of measurements. Abbreviations: AAb-IFN-α, autoantibodies against interferon-α; GADA, glutamic acid decarboxylase antibodies; LADA, latent autoimmune diabetes in adults.
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Correlation between AAb-IFN-α levels and GADA. Correlation between levels of AAb-IFN-α isoform 2b and GAD65 antibodies levels in individuals with LADA who tested positive for AAb-IFN-α2. Spearman's test was fitted to assess the monotonic covariation of measurements. Abbreviations: AAb-IFN-α, autoantibodies against interferon-α; GADA, glutamic acid decarboxylase antibodies; LADA, latent autoimmune diabetes in adults.

Journal: The Journal of Clinical Endocrinology and Metabolism

Article Title: IFN-α Neutralizing Antibodies Distinguish LADA From Early-onset Type 1 Diabetes

doi: 10.1210/clinem/dgaf001

Figure Lengend Snippet: Correlation between AAb-IFN-α levels and GADA. Correlation between levels of AAb-IFN-α isoform 2b and GAD65 antibodies levels in individuals with LADA who tested positive for AAb-IFN-α2. Spearman's test was fitted to assess the monotonic covariation of measurements. Abbreviations: AAb-IFN-α, autoantibodies against interferon-α; GADA, glutamic acid decarboxylase antibodies; LADA, latent autoimmune diabetes in adults.

Article Snippet: The antibodies directed against the following 3 isoforms of IFN-α were evaluated in sera of study participants: IFN-α1 (InvivoGen; catalog no. rcyc-hifna1), IFN-α2b (InvivoGen; catalog no. rcyc-hifna2b), IFN-α14 (PBL Assay Science, Piscataway, NJ, USA; catalog no. 11145).

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