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Journal: The Journal of Clinical Endocrinology and Metabolism
Article Title: IFN-α Neutralizing Antibodies Distinguish LADA From Early-onset Type 1 Diabetes
doi: 10.1210/clinem/dgaf001
Figure Lengend Snippet: Correlation between AAb-IFN-α levels and GADA. Correlation between levels of AAb-IFN-α isoform 2b and GAD65 antibodies levels in individuals with LADA who tested positive for AAb-IFN-α2. Spearman's test was fitted to assess the monotonic covariation of measurements. Abbreviations: AAb-IFN-α, autoantibodies against interferon-α; GADA, glutamic acid decarboxylase antibodies; LADA, latent autoimmune diabetes in adults.
Article Snippet: The antibodies directed against the following 3 isoforms of IFN-α were evaluated in sera of study participants: IFN-α1 (InvivoGen; catalog no. rcyc-hifna1),
Techniques: